Gaetti-Jardim Júnior E, Avila-Campos M J
Department of Microbiology, University of São Paulo, Brazil.
New Microbiol. 1999 Jan;22(1):63-7.
Haemagglutination and haemolytic activity of 80 Fusobacterium nucleatum isolates from human and animal origin, on different human blood types was evaluated. All the isolates were able to agglutinate erythrocytes and the most were either alpha-haemolytic or beta-haemolytic. No specificity between haemolysin or haemagglutinin and blood type was observed. Haemagglutination activity was inhibited when D-galactose, D-lactose or D-raffinose were used. Haemagglutination and haemolysis may be important factors in the pathogenesis of human and animal periodontal diseases.
对80株来自人和动物的具核梭杆菌分离株针对不同人类血型的血凝和溶血活性进行了评估。所有分离株均能凝集红细胞，且大多数为α溶血或β溶血。未观察到溶血素或血凝素与血型之间存在特异性。当使用D-半乳糖、D-乳糖或D-棉子糖时，血凝活性受到抑制。血凝和溶血可能是人和动物牙周疾病发病机制中的重要因素。
