Dickey R P
Postgrad Med. 1976 Oct;60(4):183-7. doi: 10.1080/00325481.1976.11714456.
Pubertal changes occur at a constant rate and in a particular sequence; deviations are indicative of possible menstrual problems. Such problems include precocious puberty, amenorrhea, menstrual irregularity, cramps, and premenstrual tension. Of those patients with menstrual irregularity, 10% to 15% will have chronic conditions requiring lifelong treatment.
青春期变化以恒定速率并按特定顺序发生；偏差表明可能存在月经问题。此类问题包括性早熟、闭经、月经不规律、痛经和经前紧张。在月经不规律的患者中，10%至15%会患有需要终身治疗的慢性疾病。
