McClure F D
U.S. Food and Drug Administration, Department of Health and Human Services, Washington, DC 20204, USA.
J AOAC Int. 1999 Mar-Apr;82(2):375-83.
AOAC INTERNATIONAL currently permits investigators to use the Youden Matched-Pairs Procedure to obtain estimates of the method performance indicators repeatability and reproducibility (S(r) and SR, respectively). This report explains the statistical model assumptions upon which the procedure is based, provides validity tests for several of these assumptions, explains conditions under which Youdens' "precision error" is not consistent with precision estimate S(r) or SR as defined by AOAC INTERNATIONAL, and indicates when precision estimates based on the procedure should be interpreted with caution or should not be used.
美国官方分析化学家协会（AOAC INTERNATIONAL）目前允许研究人员使用尤登配对法来获取方法性能指标重复性和再现性（分别为S(r)和SR）的估计值。本报告解释了该方法所基于的统计模型假设，对其中几个假设进行了有效性检验，解释了尤登“精密度误差”与AOAC INTERNATIONAL所定义的精密度估计值S(r)或SR不一致的情况，并指出何时应谨慎解释基于该方法的精密度估计值或不应使用这些估计值。
