Reardon M J, David T E
Baylor College of Medicine, Department of Surgery, Houston, TX 77030, USA.
Curr Opin Cardiol. 1999 Mar;14(2):104-10. doi: 10.1097/00001573-199903000-00005.
The introduction of the Starr-Edwards valve allowed complete replacement of diseased left-sided heart valves. With improved cardiopulmonary bypass, myocardial protection, and surgical techniques the mortality rate from aortic valve replacement decreased substantially, whereas the mortality rate from mitral valve replacement remained high, largely because of low cardiac output syndrome. Increasing use of mitral valve repair techniques resulted in a marked decrease in short-term and long-term morbidity and mortality when treating patients with mitral regurgitation. Some believed that this resulted from maintenance of the mitral annular papillary muscle continuity during mitral valve repair. Subsequent experimental and clinical studies have validated the positive short-term and long-term effects of maintaining the integrity of the mitral valve subvalvular apparatus. This article considers the history of the clinical use of preservation of the subvalvular apparatus, the physiologic studies examining this concept, and the clinical data available on its use. It also examines the following: 1) mitral stenosis versus mitral regurgitation and the preservation of the subvalvular apparatus; 2) whether the anterior, posterior, or both areas of the subvalvular apparatus should be preserved; and 3) the surgical techniques for the preservation of the subvalvular apparatus and valve implantation.
斯塔尔-爱德华兹瓣膜的引入使得病变的左侧心脏瓣膜能够得到完全置换。随着体外循环、心肌保护和手术技术的改进,主动脉瓣置换术的死亡率大幅下降,而二尖瓣置换术的死亡率仍然很高,这主要是由于低心排血量综合征。二尖瓣修复技术的使用增加,使得在治疗二尖瓣反流患者时,短期和长期的发病率及死亡率显著降低。一些人认为,这是因为二尖瓣修复过程中二尖瓣环乳头肌的连续性得以维持。随后的实验和临床研究证实了维持二尖瓣瓣下结构完整性的短期和长期积极效果。本文探讨了保留瓣下结构在临床应用中的历史、检验这一概念的生理学研究以及有关其应用的临床数据。它还研究了以下内容:1)二尖瓣狭窄与二尖瓣反流以及瓣下结构的保留;2)瓣下结构的前部、后部或两者是否都应保留;3)保留瓣下结构及瓣膜植入的手术技术。