Pethö B
Psychiatr Neurol Med Psychol (Leipz). 1976 Dec;28(12):738-46.
The spectrum of pharmacogenic pathomorphosis has been found to be also dependent upon the forms of disease, i.e., the special morbogenic factors. Two opposed types of nosotropy of psychopharmaceuticals, namely, protective and nosogenic nosotropy, are considered in dependence on the pharmacotherapeutic effect produced and the mode of clinical action. Protective and nosogenic nosotropy may be observed to be active simultaneously and result in characteristic paradoxes of the psychopharmacotherapy of endogenous psychoses.
已发现药物致病变态反应谱也取决于疾病形式，即特殊致病因素。根据所产生的药物治疗效果和临床作用方式，考虑精神药物的两种相反类型的致病倾向，即保护性致病倾向和致病因性致病倾向。可观察到保护性致病倾向和致病因性致病倾向同时起作用，并导致内源性精神病心理药物治疗的特征性矛盾。
