Mastroeni F, Novella G, Curti P, D'Amico A, Lusardi L, Porcaro A B, Tallarigo C
Cattedra e Divisione Clinicizzata di Urologia, Verona, Italia.
Arch Ital Urol Androl. 1999 Feb;71(1):31-4.
Fournier's gangrene is an extensive fulminant infection of the genitals, perineum or the abdominal wall. Since the first description by Jean Alfred Fournier in 1883 about 700 cases have been reported in the literature. The main aetiological factors are: perianal, perirectal or periurethral infections, diabetes mellitus and chronic alcoholism. Many aerobic and anaerobic organisms may be involved. Mortality rates range from 30-50%. The dramatic course of Fournier's gangrene requires early recognition, surgical drainage, extensive surgical debridment, antimicrobial therapy, hyperbaric oxygen therapy, as well as intensive care treatment in order to prevent irreversible endotoxic shock. We report two cases of Fournier's gangrene. In both cases symptoms were fever, pain and extensive cutaneous necrosis in the scroto-perineal region.
福尼尔坏疽是一种发生于生殖器、会阴或腹壁的广泛暴发性感染。自1883年让·阿尔弗雷德·福尼尔首次描述以来,文献中已报道了约700例病例。主要病因包括:肛周、直肠周围或尿道周围感染、糖尿病和慢性酒精中毒。许多需氧菌和厌氧菌都可能参与其中。死亡率在30%至50%之间。福尼尔坏疽的病情发展迅速,需要早期识别、手术引流、广泛的手术清创、抗菌治疗、高压氧治疗以及重症监护治疗,以防止发生不可逆的内毒素休克。我们报告了两例福尼尔坏疽病例。两例患者的症状均为发热、疼痛以及阴囊与会阴区域广泛的皮肤坏死。