Owens W E, Nickerson S C, Ray C H
Mastitis Research Laboratory, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Homer 71040, USA.
J Dairy Sci. 1999 Mar;82(3):645-7. doi: 10.3168/jds.S0022-0302(99)75279-3.
Two antibiotic preparations, tilmicosin and ceftiofur, were tested intramammarily and parenterally against Staphylococcus aureus mastitis in lactating cows. Neither product was effective as a lactating cow treatment at the doses and durations of treatment tested. Injection or infusion of tilmicosin and infusion of ceftiofur resulted in reductions of bacteria present in milk; however, only one quarter treated with infusion of tilmicosin was cured, and no cures were observed for the other treatments. Somatic cell counts were transiently reduced by infusion of ceftiofur and by infusion and injection of tilmicosin; however, they returned to pretreatment values by 28 d posttreatment.
两种抗生素制剂，替米考星和头孢噻呋，通过乳房内给药和非肠道给药方式，对泌乳奶牛的金黄色葡萄球菌性乳腺炎进行了测试。在所测试的剂量和治疗持续时间下，这两种产品作为泌乳奶牛的治疗药物均无效。注射或输注替米考星以及输注头孢噻呋可使牛奶中的细菌数量减少；然而，仅用替米考星输注治疗的四分之一乳房治愈，其他治疗未观察到治愈情况。输注头孢噻呋以及输注和注射替米考星可使体细胞计数暂时降低；然而，在治疗后28天，它们又恢复到治疗前的值。
