Zepeda A, Montiel T, Brailowsky S
Department of Neurosciences, Institute of Cellular Physiology, Universidad Nacional Autónoma de México, Mexico City.
J Neurotrauma. 1999 Mar;16(3):267-71. doi: 10.1089/neu.1999.16.267.
The present work aimed at studying the participation of the homologous contralateral zone to a unilateral somatomotor cortex lesion, once the animals had showed a significant functional recovery. We studied recovery of coordinated walking after unilateral motor cortex aspiration in rats. A callosotomy was performed 20 days after the initial lesion, without significant effects. We conclude that after this time period, the intact hemisphere plays no role in the recovery process, suggesting that at this time point recovery does not depend on the integrity of corpus callosal fibers at this rostral-caudal level.
本研究旨在探讨在动物已表现出显著功能恢复后，同侧对侧区域在单侧躯体运动皮层损伤中的参与情况。我们研究了大鼠单侧运动皮层损毁后协调行走的恢复情况。在初始损伤20天后进行胼胝体切开术，未产生显著影响。我们得出结论，在此时间段后，完整的半球在恢复过程中不起作用，这表明在这个时间点，恢复不依赖于该头尾水平胼胝体纤维的完整性。
