Oster G, Wang H
Departments of Molecular & Cellular Biology, College of Natural Resources, University of California, Berkeley, California 94720-3112, USA.
Structure. 1999 Apr 15;7(4):R67-72. doi: 10.1016/s0969-2126(99)80046-x.
FoF1 ATPase is the universal protein responsible for ATP synthesis. The enzyme comprises two reversible rotary motors: Fo is either an ion 'turbine' or an ion pump, and F1 is either a hydrolysis motor or an ATP synthesizer. Recent biophysical and biochemical studies have helped to elucidate the operating principles for both motors.
F₀F₁ ATP 合酶是负责 ATP 合成的通用蛋白。该酶由两个可逆旋转马达组成:F₀ 要么是离子“涡轮机”,要么是离子泵,而 F₁ 要么是水解马达,要么是 ATP 合成器。最近的生物物理和生化研究有助于阐明这两个马达的工作原理。