Oster George, Wang Hongyun
Depts Molecular and Cellular Biology and ESPM, College of Natural Resources, University of California, Berkeley, CA 94720, USA.
Trends Cell Biol. 2003 Mar;13(3):114-21. doi: 10.1016/s0962-8924(03)00004-7.
Three protein motors have been unambiguously identified as rotary engines: the bacterial flagellar motor and the two motors that constitute ATP synthase (F(0)F(1) ATPase). Of these, the bacterial flagellar motor and F(0) motors derive their energy from a transmembrane ion-motive force, whereas the F(1) motor is driven by ATP hydrolysis. Here, we review the current understanding of how these protein motors convert their energy supply into a rotary torque.
细菌鞭毛马达以及构成ATP合酶(F(0)F(1) ATP酶)的两种马达。其中,细菌鞭毛马达和F(0)马达从跨膜离子动力中获取能量,而F(1)马达则由ATP水解驱动。在此,我们综述了目前对这些蛋白质马达如何将其能量供应转化为旋转扭矩的理解。