Bassler T J, Orozco R, Bassler I C, Boyle L M, Bormes T
UroDiagnostics Division, UroCor Inc., Oklahoma City, Oklahoma, USA.
Urology. 1999 Apr;53(4):832-4. doi: 10.1016/s0090-4295(98)00418-x.
We diagnosed prostatic adenosquamous carcinoma by prostate core needle biopsy in a 55-year-old man with no history of prostate cancer. The prognosis, DNA analysis, and histogenesis of this extremely rare tumor are controversial. To our knowledge, this is the first case of adenosquamous carcinoma diagnosed by core needle biopsy in a patient with no history of prostate cancer or hormonal therapy. We performed immunohistologic and DNA analysis to further characterize this cancer. The clinical presentation and abnormal DNA analysis portend an aggressive course.
我们通过前列腺穿刺活检诊断出一名55岁、无前列腺癌病史男性患有前列腺腺鳞癌。这种极其罕见肿瘤的预后、DNA分析及组织发生存在争议。据我们所知，这是首例在无前列腺癌病史或激素治疗史的患者中通过穿刺活检诊断出的腺鳞癌病例。我们进行了免疫组织化学和DNA分析以进一步明确这种癌症的特征。临床表现及异常的DNA分析预示着病情进展迅速。
