Matsko D E, Korshunov A G, Sokolova I A, Lakhteeva S V, Nikitin P I
A. L. Polenov Neurosurgical Institute, St-Petersburg, Moscow.
Arkh Patol. 1999 Jan-Feb;61(1):30-5.
242 cases of brain arterio-venous malformations (AVM) are analysed clinically and anatomically. Their pathology, histological, ultrastructural and immunohistochemical characteristics, therapeutic pathomorphosis are described. The concept is suggested according to which AVM is a collective term including true developmental defects, dysembryogenetic tumors and outcomes of various pathologic processes (trauma, brain circulation and compensatory-adaptive disturbances, etc.). The necessity of therapeutic methods corrections in agreement with the disease pathogenesis is outlined.
对242例脑动静脉畸形（AVM）进行了临床和解剖学分析。描述了它们的病理学、组织学、超微结构和免疫组化特征以及治疗后的病理形态变化。提出了一个概念，即AVM是一个统称，包括真正的发育缺陷、胚胎发育异常肿瘤以及各种病理过程（创伤、脑循环和代偿适应性障碍等）的结果。概述了根据疾病发病机制进行治疗方法调整的必要性。
