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[征兵年龄人群中乙肝和丙肝病毒“携带者”的肝脏变化]

[Liver changes in people of conscription age--"carriers" of hepatitis B and C viruses].

作者信息

Povzun S A, Chirskiĭ V S, Zhdanov K V

机构信息

Military Medical Academy, St. Petersburg.

出版信息

Arkh Patol. 1999 Jan-Feb;61(1):36-9.

Abstract

89 liver needle biopsies from young persons--HBV and HCV carriers--were studied histologically, immunohistochemically, morphometrically and electron microscopically. Groups with compensatory-adaptive and degenerative liver lesions, those with mild manifestations of a chronic virus infection, and those with chronic hepatitis of minimal and weak activity were identified. Latent chronic hepatitis is found in 68.5% of HBV and HCV carriers. Morphological picture of HCV infection is more pronounced as compared to that of HBV infection. The role of eosinophils in the development of hepatitis B and C forms lacking clinical symptoms is demonstrated.

摘要

对89例来自年轻人的肝穿刺活检标本(乙肝和丙肝携带者)进行了组织学、免疫组织化学、形态计量学及电子显微镜检查。识别出具有代偿适应性和退行性肝损伤的组、慢性病毒感染轻度表现的组以及最小和轻度活动度的慢性肝炎组。在68.5%的乙肝和丙肝携带者中发现了潜伏性慢性肝炎。与乙肝感染相比,丙肝感染的形态学表现更为明显。证实了嗜酸性粒细胞在无症状乙肝和丙肝形式发展中的作用。

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