Sawin P D, Theodore N, Rekate H L
Department of Neurological Surgery, Barrow Neurological Institute, and St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA..
J Neurosurg. 1999 Apr;90(2 Suppl):231-3. doi: 10.3171/spi.1999.90.2.0231.
Gangliogliomas of the spinal cord are rare disease entities that occur in early childhood. Their occurrence in association with neurofibromatosis Type 2 (NF2) has not been described. The authors describe the unique case of a 2-year-old child with stigmata of NF2 who harbored a spinal cord ganglioglioma that presented as a rapidly growing, exophytic intramedullary mass lesion at the cervicomedullary junction. Treatment consisted of complete surgical resection. Histopathological analysis of the lesion demonstrated a mixed population of neoplastic cells, of both neuronal and glial lineage, that supported the diagnosis of ganglioglioma.
脊髓节细胞胶质瘤是一种罕见的疾病实体，多发生于儿童早期。此前尚未有其与2型神经纤维瘤病（NF2）相关的病例报道。本文作者描述了一例独特病例，一名2岁患有NF2特征的儿童，其脊髓节细胞胶质瘤表现为颈髓交界处快速生长的髓外性髓内肿块病变。治疗方式为完整手术切除。对该病变的组织病理学分析显示，肿瘤细胞由神经元和神经胶质细胞谱系混合组成，支持节细胞胶质瘤的诊断。
