Wolf R W, Schultze D, Fretz C, Weissert M, Waibel P
Institut für Radiologie, Kantonsspital St. Gallen, Switzerland.
Pediatr Radiol. 1999 Mar;29(3):191-3. doi: 10.1007/s002470050570.
This case report demonstrates the course of herpes simplex virus cerebritis in a patient aged 7 years 2 months who presented with non-specific symptoms followed by an epileptic attack. Subcortical, bilateral opercular and bilateral thalamic lesions were detected, but the temporal and inferior frontal lobes were spared. The patient developed anarthria, impairment of mastication and swallowing consistent with operculum syndrome. Diagnosis was made by magnetic resonance imaging and elevation of oligoclonal antibodies specific to herpes simplex virus in cerebrospinal fluid after an unexpectedly negative polymerase chain reaction test.
本病例报告展示了一名7岁2个月患者的单纯疱疹病毒性脑炎病程，该患者最初出现非特异性症状，随后发生癫痫发作。检测到双侧岛叶皮质下及双侧丘脑病变，但颞叶和额下回未受累。患者出现构音障碍、咀嚼和吞咽功能受损，符合岛叶综合征。诊断通过磁共振成像以及在聚合酶链反应检测意外呈阴性后，脑脊液中单纯疱疹病毒特异性寡克隆抗体升高得以明确。
