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葡萄膜炎患者白内障手术后视觉预后的评估。

Assessment of visual outcome after cataract surgery in patients with uveitis.

作者信息

Okhravi N, Lightman S L, Towler H M

机构信息

Department of Ophthalmology, Moorfields Eye Hospital and the Institute of Ophthalmology, London, England, UK.

出版信息

Ophthalmology. 1999 Apr;106(4):710-22. doi: 10.1016/S0161-6420(99)90155-0.

Abstract

OBJECTIVE

To assess the outcome of cataract surgery in eyes of patients with uveitis.

DESIGN

Prospective, noncomparative case series.

PARTICIPANTS

A total of 90 eyes of 76 patients fulfilled the enrollment criteria.

INTERVENTION

All patients had their surgery performed using standard cataract extraction techniques. Unless contraindicated, preoperative systemic steroids were administered to all patients with posterior disease, chronic anterior uveitis, with known macular edema, and those in whom outcome of cataract surgery on the fellow eye had been poor.

RESULTS

Patients were divided into those with anterior disease (n = 53) and those with posterior disease (n = 37). Overall, 81 (90%) of 90 eyes showed improvement in vision (median +4 Snellen lines). In those with anterior disease, the development of severe uveitis in the first week postsurgery was associated with a greater incidence of macular edema (P = 0.014). The single largest diagnosis in those with posterior disease was that of panuveitis (n = 24). This group showed the poorest visual outcomes in this study. The majority of patients, however, were noted to have visual loss secondary to conditions present before surgery.

CONCLUSION

Cataract surgery in eyes with uveitis leads to an improvement of vision in the majority of cases. Severe postoperative uveitis is the most common postoperative complication and is associated with a significant risk of macular edema in those with anterior disease. In the posterior group, poor visual outcome after surgery is most commonly the result of preoperative vision-limiting conditions.

摘要

目的

评估葡萄膜炎患者眼部白内障手术的效果。

设计

前瞻性、非对照病例系列研究。

参与者

76例患者共90只眼符合纳入标准。

干预措施

所有患者均采用标准白内障摘除技术进行手术。除非有禁忌证,所有患有后部疾病、慢性前葡萄膜炎、已知黄斑水肿以及对侧眼白内障手术效果不佳的患者术前均给予全身类固醇治疗。

结果

患者分为前部疾病组(n = 53)和后部疾病组(n = 37)。总体而言,90只眼中有81只(90%)视力改善(平均提高4行斯内伦视力表视力)。在前部疾病组中,术后第一周严重葡萄膜炎的发生与黄斑水肿的发生率较高相关(P = 0.014)。后部疾病组中最常见的诊断是全葡萄膜炎(n = 24)。该组在本研究中视力预后最差。然而,大多数患者的视力丧失是由手术前存在的疾病导致的。

结论

葡萄膜炎患者的白内障手术在大多数情况下可改善视力。严重的术后葡萄膜炎是最常见的术后并发症,并且在前部疾病患者中与黄斑水肿的显著风险相关。在后部疾病组中,手术后视力预后不佳最常见的原因是术前限制视力的疾病。

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