First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines.
作者信息
Kim D H, Jin Y
机构信息
Center for Biofunctional Molecules and Department of Chemistry, Pohang University of Science and Technology, Korea.
出版信息
Bioorg Med Chem Lett. 1999 Mar 8;9(5):691-6. doi: 10.1016/s0960-894x(99)00055-4.
Abstract
A series of N-acyl-N-hydroxy-beta-Phe were designed, synthesized, and shown to have potent inhibitory activity for carboxypeptidase A (CPA). They are the first examples of CPA inhibitors having a hydroxamate functionality.
摘要
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