Shiha G, El-Sayed S S
Department of Internal Medicine, El-Mansoura University, El-Mansoura, Egypt.
Gastrointest Endosc. 1999 Apr;49(4 Pt 1):437-41. doi: 10.1016/s0016-5107(99)70039-8.
Gastric variceal bleeding is a serious complication of portal hypertension. The role of endoscopy in its management is still controversial. However, band ligation of gastric varices has not been evaluated. This study prospectively describes gastric variceal ligation as a new endoscopic technique for the management of different types of gastric varices.
Gastric variceal ligation was performed in 27 patients with gastric varices: 3 patients had type 1 gastroesophageal varices, 14 had type 2, 8 had isolated gastric varices, and 2 had both type 1 and type 2 gastroesophageal varices. The etiology of portal hypertension was schistosomiasis in 9, post hepatic cirrhosis in 3, and mixed cirrhosis in 15 patients. The Child-Pugh classification was grade A in 6, B in 17, and C in 4 cases. Active variceal bleeding was present in 18 patients, whereas nonbleeding varices were encountered in 9 patients.
Emergency gastric variceal ligation arrested bleeding in 16 of 18 patients (88.8%). Recurrent bleeding was noted in 5 of 27 (18.5%). Six patients died (22.2%), 3 due to recurrent bleeding and 2 to liver failure. Variceal obliteration was achieved in all patients who underwent repeated elective sessions. The number of sessions needed for obliteration of varices was significantly less in patients with isolated gastric varices when compared with those with type 1 gastroesophageal varices ( p < 0.04). No serious complications occurred.
Gastric variceal ligation is a safe and effective treatment for the different types of gastric varices but especially isolated gastric varices.
胃静脉曲张出血是门静脉高压的严重并发症。内镜检查在其治疗中的作用仍存在争议。然而,胃静脉曲张套扎术尚未得到评估。本研究前瞻性地描述了胃静脉曲张套扎术作为一种治疗不同类型胃静脉曲张的新内镜技术。
对27例胃静脉曲张患者实施胃静脉曲张套扎术:3例为1型胃食管静脉曲张,14例为2型,8例为孤立性胃静脉曲张,2例同时有1型和2型胃食管静脉曲张。门静脉高压的病因在9例患者中为血吸虫病,3例为肝后性肝硬化,15例为混合性肝硬化。Child-Pugh分级6例为A级,17例为B级,4例为C级。18例患者存在活动性静脉曲张出血,9例患者为非出血性静脉曲张。
18例患者中的16例(88.8%)通过急诊胃静脉曲张套扎术止血。27例患者中有5例(18.5%)出现再出血。6例患者死亡(22.2%),3例死于再出血,2例死于肝功能衰竭。所有接受重复择期手术的患者静脉曲张均消失。与1型胃食管静脉曲张患者相比,孤立性胃静脉曲张患者静脉曲张消失所需的手术次数明显更少(p < 0.04)。未发生严重并发症。
胃静脉曲张套扎术是治疗不同类型胃静脉曲张尤其是孤立性胃静脉曲张的一种安全有效的方法。