[大鼠中由N-亚硝基-N-甲基脲诱导的膀胱乳头状瘤]
[Papillomas of the urinary bladder induced by N-nitroso-N-methylurea in rats].
作者信息
Vlasov N N, Balanski R M, Khudoleĭ V V
出版信息
Vopr Onkol. 1976;22(12):58-61.
PMID:1020258
Abstract
N-nitroso-N-methylurea (a total dosage--6 mg per animal), administered by a catheter in the urinary bladder cavity in female rats, following 9--56 weeks induced in 16 of 23 rats tumors of the vesical mucous membrane (mostly transitional cell papillomas).
摘要
用导管将N-亚硝基-N-甲基脲（每只动物总剂量为6毫克）注入雌性大鼠的膀胱腔内，9至56周后，23只大鼠中有16只诱发了膀胱黏膜肿瘤（大多为移行细胞乳头状瘤）。
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