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供体钠水平对受体肝移植肝功能的影响。

The effects of donor sodium levels on recipient liver graft function.

作者信息

Van da Walker S G

机构信息

Donor Alliance, Inc, Denver, Colo., USA.

出版信息

J Transpl Coord. 1998 Dec;8(4):205-8.

PMID:10205459
Abstract

A great deal of discussion has been generated regarding the effects of donor hypernatremia on recipient liver graft function. Much of this discussion is anecdotal and focuses on the detrimental effects of hypernatremia in the organ donor. The treatment of donor hypernatremia often leads to changes in donor management protocols. A retrospective study was conducted to determine if donor hypernatremia measurably alters the liver graft function of recipients. Results indicated that donor sodium values were unrelated to any recipient parameter assessed. Although further studies are pending, these findings suggest that a moderate rather than a severe approach to the management of donor hypernatremia may be preferred.

摘要

关于供体高钠血症对受体肝移植功能的影响,已经引发了大量讨论。其中很多讨论都是基于轶事的,并且聚焦于高钠血症对器官供体的有害影响。供体高钠血症的治疗常常导致供体管理方案的改变。进行了一项回顾性研究,以确定供体高钠血症是否会显著改变受体的肝移植功能。结果表明,供体钠值与所评估的任何受体参数均无关联。尽管有待进一步研究,但这些发现表明,对于供体高钠血症的管理,采用适度而非严格的方法可能更为可取。

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