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[免疫与神经记忆之间的相互关系:免疫刺激期间大鼠的学习能力]

[Interrelationship between immunologic and neurologic memory: learning ability of rats during immunostimulation].

作者信息

Ashmarin I P, Eropkin M Iu, Maliukova I V

出版信息

Zh Evol Biokhim Fiziol. 1976 Nov-Dec;12(6):509-13.

PMID:1020549
Abstract

Studies have been made on the effect of an immunostimulator - the complete Freund's adjuvant - upon the learning ability in Wistar rats for visual discrimination using food-obtaining and avoidance of the electric shock techniques. Injection of the adjuvant significantly increases learning ability provided negative reinforcement technique is used, but inhibits the former under the conditions of positive reinforcement. Analysis of the extinction of the conditioned reflexes yielded similar results. Possible relation of immunogenesis to the formation of memory is discussed.

摘要

已经对一种免疫刺激剂——完全弗氏佐剂——对Wistar大鼠利用获取食物和避免电击技术进行视觉辨别学习能力的影响进行了研究。注射佐剂在使用负强化技术时显著提高学习能力,但在正强化条件下会抑制学习能力。对条件反射消退的分析得出了类似的结果。文中讨论了免疫发生与记忆形成之间可能的关系。

相似文献

1
[Interrelationship between immunologic and neurologic memory: learning ability of rats during immunostimulation].[免疫与神经记忆之间的相互关系:免疫刺激期间大鼠的学习能力]
Zh Evol Biokhim Fiziol. 1976 Nov-Dec;12(6):509-13.
2
Relations between immunological and neurological memory: learning ability in rats during immunostimulation.免疫记忆与神经记忆之间的关系:免疫刺激期间大鼠的学习能力。
Neurosci Behav Physiol. 1978 Jan-Mar;9(1):83-6. doi: 10.1007/BF01182661.
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[The action on brain functions in white rats of the immunostimulant Freund's complete adjuvant].[免疫刺激剂弗氏完全佐剂对白鼠脑功能的作用]
Nauchnye Doki Vyss Shkoly Biol Nauki. 1992(3):97-103.
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Success of autonomic operant conditioning of heart rate without involving contractions of somatic skeletal muscles.不涉及躯体骨骼肌收缩的心率自主操作性条件反射的成功。
Indian J Physiol Pharmacol. 1988 Oct-Dec;32(4):231-51.
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[Trainability of rats with positive and negative reinforcements during nonspecific stimulation of immune processes].[在免疫过程非特异性刺激期间正负强化对大鼠的可训练性]
Dokl Akad Nauk SSSR. 1976;229(3):761-3.
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Comparison of the mGluR1 antagonist A-841720 in rat models of pain and cognition.代谢型谷氨酸受体1拮抗剂A-841720在大鼠疼痛与认知模型中的比较
Behav Pharmacol. 2007 Jul;18(4):273-81. doi: 10.1097/FBP.0b013e3281f19c18.
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Adjuvant regulation of T cell function.T细胞功能的辅助调节
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[The mechanism stimulation of viral leukemogenesis by complete Freund's adjuvant].[完全弗氏佐剂刺激病毒性白血病发生的机制]
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Effect of epididymal administration of Freund's complete adjuvant on autoimmune response to spermatozoa in vasectomized rats.附睾注射弗氏完全佐剂对输精管结扎大鼠精子自身免疫反应的影响。
Indian J Exp Biol. 1984 Jul;22(7):363-6.
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[The neurotropic effects developing on the administration of Freund's complete adjuvant (FCA) to rats].[给大鼠注射弗氏完全佐剂(FCA)后产生的亲神经效应]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Jul-Aug;45(4):817-8.

引用本文的文献

1
Activity of nucleases in the rat brain during training with emotionally varying reinforcement.在伴有情绪变化强化的训练过程中大鼠脑内核酶的活性
Neurosci Behav Physiol. 1981 Jul-Aug;11(4):313-7. doi: 10.1007/BF01184191.
2
Selective depression of neuronal excitability during habituation.习惯化过程中神经元兴奋性的选择性抑制。
Neurosci Behav Physiol. 1980 Jul-Aug;10(4):333-9. doi: 10.1007/BF01184046.