[酶与改性苯乙烯-马来酸酐共聚物的偶联]
[Coupling of enzymes to modified styrene-maleic anhydride copolymers].
作者信息
Berger R, Gomoll M, Langhammer G
出版信息
Acta Biol Med Ger. 1976;35(10):1259-65.
PMID:1020563
Abstract
A copolymer of styrene and maleic anhydride is modified with low molecular weight polyoles in a very convenient manner, so that it can be applied as a carried for the fixation of biologically active compounds without further pretreatment. The modified products show storage stability over a long time without loss of coupling capacity. Examples for the fixation of trypsin, alkaline phosphatase and a bacterial glutamate dehydrogenase are given, and some properties of the resulting enzyme products are described.
摘要
苯乙烯与马来酸酐的共聚物可以很方便地用低分子量多元醇进行改性，这样它无需进一步预处理就可作为固定生物活性化合物的载体。改性产物显示出长时间的储存稳定性，且偶联能力不会丧失。文中给出了固定胰蛋白酶、碱性磷酸酶和细菌谷氨酸脱氢酶的实例，并描述了所得酶产物的一些性质。
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