Lampe D, Mai I
Acta Biol Med Ger. 1976;35(10):1341-6.
The influence of verapamil, theophylline, and papaverine on the cumulative calcium dose-effect curve was studied at the isolated perfused rat tail. The results indicate different changes of the contraction and relexation phase respectively. The findings are discussed in connection with the action mechanism of the drugs and the processes of excitation-contraction coupling.
在离体灌流的大鼠尾部研究了维拉帕米、茶碱和罂粟碱对累积钙剂量-效应曲线的影响。结果分别表明收缩期和舒张期有不同变化。结合药物作用机制和兴奋-收缩偶联过程对这些发现进行了讨论。