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Acute self-poisoning with phenformin.

作者信息

Coronho V, da Silva O A, López M

出版信息

Acta Diabetol Lat. 1976 May-Aug;13(3-4):130-3. doi: 10.1007/BF02581256.

DOI:10.1007/BF02581256
PMID:1020609
Abstract

The case is reported of a non-diabetic young woman who attempted suicide by ingesting 2,500 mg of phenformin. The most marked clinical and laboratory findings during the first 24 hrs included nausea, vomiting, anxiety, agitation, polydipsia, polyuria, increased appetite, tachycardia, tachypnea, persistent lactic acidosis, hypoglycemia and hypokalemia. Treatment at the ICU 10 hrs after ingestion of the overdose was essentially symptomatic and included measures to correct acidosis and hypoglycemia. The patient recovered completely.

摘要

相似文献

1
Acute self-poisoning with phenformin.
Acta Diabetol Lat. 1976 May-Aug;13(3-4):130-3. doi: 10.1007/BF02581256.
2
Phenformin, hypoglycemia and lactic acidosis. Report of attempted suicide.
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3
Fatal self-poisoning with phenformin.苯乙双胍致死性自服中毒。
Br Med J. 1970 Sep 26;3(5725):752. doi: 10.1136/bmj.3.5725.752.
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The interaction between alcohol, chlorpropamide and phenformin in a severe combined poisoning: case report.
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Phenformin intoxication resulting in lactic acidosis.苯乙双胍中毒导致乳酸性酸中毒。
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7
Hemodialysis for phenformin associated lactic acidosis.
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[Lactic acidosis and phenformin].
Union Med Can. 1976 Dec;105(12):1810-4.
9
Phenformin and lactic acidosis in a diabetic and a nondiabetic.
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[Interaction between phenformin and alcohol. Lactic acidosis and hypoglycemia in patients with stable diabetes mellitus].
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本文引用的文献

1
The mechanism of action of hypoglycemic guanidine derivatives.降血糖胍衍生物的作用机制。
Diabetes. 1960 May-Jun;9:170-3. doi: 10.2337/diab.9.3.170.
2
Irreversible lactic acidosis associated with phenformine therapy. Report of three cases.与苯乙双胍治疗相关的不可逆性乳酸性酸中毒。三例报告。
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Phenformin, hypoglycemia and lactic acidosis. Report of attempted suicide.
N Engl J Med. 1966 Oct 20;275(16):886-8. doi: 10.1056/NEJM196610202751606.
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Attempted suicide with phenformin.
Diabetes. 1965 Dec;14(12):811-2. doi: 10.2337/diab.14.12.811.
8
Phenformin intoxication resulting in lactic acidosis.苯乙双胍中毒导致乳酸性酸中毒。
Johns Hopkins Med J. 1971 May;128(5):278-81.
9
Fatal self-poisoning with phenformin.苯乙双胍致死性自服中毒。
Br Med J. 1970 Sep 26;3(5725):752. doi: 10.1136/bmj.3.5725.752.
10
Fatal lactic acidosis after an overdose of phenformin.苯乙双胍过量导致致命性乳酸性酸中毒。
Br Med J. 1967 Oct 28;4(5573):216. doi: 10.1136/bmj.4.5573.216.