一种改进的气相色谱法用于测定尿中木糖醇、葡萄糖醛酸、葡萄糖二酸、古洛糖酸和抗坏血酸，并给出了它们在大鼠、兔、豚鼠和狨猴体内的值。
An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset.
作者信息
Warrander A, Waring R H
出版信息
Xenobiotica. 1978 Oct;8(10):605-9. doi: 10.3109/00498257809069572.
PMID:102085
Abstract
- Urinary levels of xylitol and glucuronic, glucaric, gulonic and ascorbic acids were measured in the rat, rabbit, guinea-pig and marmoset by an improved g.l.c. technique. 2. Administration of a compound (2-methylbenzanilide) known to be conjugated and excreted as a beta-glucuronide had some effect on the output of these compounds of the glucuronic acid pathway in all four species, and caused a significant decrease in gulonic acid in the rat.
摘要
- 采用改良的气相色谱技术测定了大鼠、兔、豚鼠和狨猴尿液中木糖醇以及葡萄糖醛酸、葡萄糖二酸、古洛糖酸和抗坏血酸的含量。2. 给予一种已知会以β-葡萄糖醛酸苷形式结合并排泄的化合物（2-甲基苯甲酰苯胺），对所有这四个物种的葡萄糖醛酸途径中这些化合物的排出量均有一定影响，并导致大鼠体内古洛糖酸显著减少。
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