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一种改进的气相色谱法用于测定尿中木糖醇、葡萄糖醛酸、葡萄糖二酸、古洛糖酸和抗坏血酸,并给出了它们在大鼠、兔、豚鼠和狨猴体内的值。

An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset.

作者信息

Warrander A, Waring R H

出版信息

Xenobiotica. 1978 Oct;8(10):605-9. doi: 10.3109/00498257809069572.

DOI:10.3109/00498257809069572
PMID:102085
Abstract
  1. Urinary levels of xylitol and glucuronic, glucaric, gulonic and ascorbic acids were measured in the rat, rabbit, guinea-pig and marmoset by an improved g.l.c. technique. 2. Administration of a compound (2-methylbenzanilide) known to be conjugated and excreted as a beta-glucuronide had some effect on the output of these compounds of the glucuronic acid pathway in all four species, and caused a significant decrease in gulonic acid in the rat.
摘要
  1. 采用改良的气相色谱技术测定了大鼠、兔、豚鼠和狨猴尿液中木糖醇以及葡萄糖醛酸、葡萄糖二酸、古洛糖酸和抗坏血酸的含量。2. 给予一种已知会以β-葡萄糖醛酸苷形式结合并排泄的化合物(2-甲基苯甲酰苯胺),对所有这四个物种的葡萄糖醛酸途径中这些化合物的排出量均有一定影响,并导致大鼠体内古洛糖酸显著减少。

相似文献

1
An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset.一种改进的气相色谱法用于测定尿中木糖醇、葡萄糖醛酸、葡萄糖二酸、古洛糖酸和抗坏血酸,并给出了它们在大鼠、兔、豚鼠和狨猴体内的值。
Xenobiotica. 1978 Oct;8(10):605-9. doi: 10.3109/00498257809069572.
2
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Jpn J Pharmacol. 1974 Dec;24(6):869-78. doi: 10.1254/jjp.24.869.
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Urinary excretion of D-glucaric acid, total glucuronic acid and total porphyrins in porphyria cutanea tarda.
Acta Hepatogastroenterol (Stuttg). 1978 Aug;25(4):267-70.
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Direct determination of D-[U-14C] glucaric acid in urine by ion-exchange high-performance liquid chromatography.采用离子交换高效液相色谱法直接测定尿液中的D-[U-14C]葡萄糖二酸。
J Chromatogr. 1983 Aug 12;276(1):163-8. doi: 10.1016/s0378-4347(00)85077-x.
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HPLC determination of D-glucaric acid in human urine.高效液相色谱法测定人尿中D-葡萄糖二酸
J Anal Toxicol. 1993 May-Jun;17(3):146-50. doi: 10.1093/jat/17.3.146.
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[Non-dialyzable beta-glucuronidase inhibitor in guinea-pig urine. I. Purification (author's transl)].豚鼠尿液中不可透析的β-葡萄糖醛酸酶抑制剂。I. 纯化(作者译)
Yakugaku Zasshi. 1975 Oct;95(10):1226-33.
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The excretion of metabolites of the D-glucuronic acid pathway in human urine. Effect of phenobarbitone administration.
Xenobiotica. 1982 Apr;12(4):241-7. doi: 10.3109/00498258209052462.
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An evaluation of urinary D-glucaric acid excretion during acute hepatitis in man.人体急性肝炎期间尿中D-葡糖二酸排泄情况的评估。
Am J Dig Dis. 1978 Jan;23(1):18-22. doi: 10.1007/BF01072570.
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Improved determination of D-glucaric acid in urine.尿液中D-葡萄糖二酸测定方法的改进。
Clin Chem. 1981 Mar;27(3):422-6.
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Responses of the D-glucuronic acid pathway in rat tissues to treatment with tetrachlorodibenzodioxin.大鼠组织中D-葡萄糖醛酸途径对四氯二苯并二恶英处理的反应。
Xenobiotica. 1978 Jul;8(7):397-402. doi: 10.3109/00498257809070023.