Afanas'eva V M, Pokrovskaia L Ia, Leonova L V
Arkh Patol. 1976;38(10):12-8.
Analysis of section material was carried out covering the period 1943-1975. It was established that proportion of septic diseases in the general structure of children's mortality in the recent years was stabilized at rather high levels (1973-1975--17.1%). Fatal outcomes were most often among infants at the early period of life in whom sepsis developed against the background of premorbid factors including prematurity, malformations, pathologic labour, mother's diseases, etc. The course of sepsis was particularly severe in infants with congenital immunodeficient states. The main pathogene of sepsis at present is staphylococcus. During the period under study, correlation and morphology of various forms of sepsis varied depending upon the pathogene and therapy applied. Since 1968 and up to new the most common form of sepsis has been that morphologically identical to sepsis observed in 1943-1947, i.e. before the wide application of antibiotics.
对1943年至1975年期间的切片材料进行了分析。结果表明,近年来败血症在儿童死亡总结构中的比例稳定在相当高的水平(1973 - 1975年为17.1%)。死亡结果最常发生在生命早期的婴儿中,这些婴儿在包括早产、畸形、病理分娩、母亲疾病等病前因素的背景下发生败血症。败血症的病程在先天性免疫缺陷状态的婴儿中尤为严重。目前败血症的主要病原体是葡萄球菌。在研究期间,各种形式败血症的相关性和形态学根据病原体和应用的治疗方法而有所不同。自1968年以来直至现在,最常见的败血症形式在形态上与1943 - 1947年(即抗生素广泛应用之前)观察到的败血症相同。