Vtiurin B V, Kaem R I
Arkh Patol. 1976;38(6):27-33.
Electron-microscopy investigations of the small intestine mucosa in white rats with deep thermal burns of 18-20% of the body surface showed that already in early periods following the trauma grave thermal burns caused structural desorganization of the enterocytic barrier and invasion of the intestinal microflora. Damages of the wall of capillaries of the small intestine mucosa, being in themselves manifestations of generalized lesion of the histo-hematic barriers in burns, contributed to further invasion of microflora and its vital activity products into the blood. During the investigation a morphological picture of the phenomenon of endotoxinemia and bacteriemia developed already in the early periods of the burn trauma was established.
对体表18 - 20%深度热烧伤的白色大鼠小肠黏膜进行电子显微镜检查发现，在创伤后的早期，严重的热烧伤就已导致肠细胞屏障的结构紊乱和肠道微生物群的侵入。小肠黏膜毛细血管壁的损伤本身就是烧伤时组织 - 血液屏障全身性损伤的表现，它促使微生物群及其生命活动产物进一步侵入血液。在研究过程中，证实了在烧伤创伤早期就已出现内毒素血症和菌血症现象的形态学表现。
