Maalej M, Frikha H, Ben Salem S, Daoud J, Bouaouina N, Ben Abdallah M, Ben Romdhane K
Service de radiothérapie, Institut Salah-Azaiz de cancérologie, boulevard du 9-Avril, Bab Saadoun, 1006 Tunis, Tunisie.
Bull Cancer. 1999 Mar;86(3):302-6.
This study has been realized to determine epidemiological profile and clinicopathologic aspect of breast cancer in Tunisia. We have counted and analyzed all cancers of the breast diagnosed in Tunisia with proof pathologic or to defect cytologic of malignancy, between first January 1994 and 31 December 1994. In the course of this year, 689 new cases of mammary cancers have been diagnosed at the women. The average patient age was 50.0 years, the incidence standardized on the age of the cancer of the breast in Tunisia was 16.7/100,000 women. The average size of the tumor was 49.5 mm (35.8 mm at patients processed in private clinics and 50.7 mm at patients processed in the public hospitals). According to TNM classification of 1988, 7.2% of tumors were classified T1, 48.9% T2, 18.5% T3, and 23.4% T4 (6.2% T4d and 16.1% T4b). 22.1% of tumors were M1. 3.3% were in situ carcinoma. For the infiltrants cancers, the grade II SBR has been the most frequent (53.6%). On the therapeutic plan, the conservative processing has been practiced only at 17.6% of patients. The cancer of the breast in Tunisia rest again relatively little frequent, and its clinic profile resides alarming. The inflammatory cancer notion of the breast (equal T4d) intimately linked to Tunisia overestimates probably the reality. Cancers that were classified "PEV" in many publications would be in reality only for most of locally evolved and neglected cancers.
本研究旨在确定突尼斯乳腺癌的流行病学特征和临床病理情况。我们统计并分析了1994年1月1日至1994年12月31日期间在突尼斯诊断出的所有经病理证实或恶性细胞学检查确诊的乳腺癌病例。在这一年中,共诊断出689例女性乳腺癌新病例。患者的平均年龄为50.0岁,突尼斯乳腺癌年龄标准化发病率为16.7/10万女性。肿瘤的平均大小为49.5毫米(私立诊所接受治疗的患者为35.8毫米,公立医院接受治疗的患者为50.7毫米)。根据1988年的TNM分类,7.2%的肿瘤为T1期,48.9%为T2期,18.5%为T3期,23.4%为T4期(6.2%为T4d期,16.1%为T4b期)。22.1%的肿瘤为M1期。3.3%为原位癌。对于浸润性癌,II级SBR最为常见(53.6%)。在治疗方案上,仅17.6%的患者采用了保守治疗。突尼斯的乳腺癌发病率仍然相对较低,但其临床特征令人担忧。与突尼斯密切相关的乳腺炎性癌概念(等同于T4d期)可能高估了实际情况。许多出版物中分类为“PEV”的癌症实际上可能大多是局部进展且被忽视的癌症。