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[突尼斯的乳腺癌:流行病学特征及发病率趋势]

[Breast cancer in Tunisia: epidemiologic characteristics and trends in incidence].

作者信息

Ben Abdallah M, Zehani S, Maalej M, Hsairi M, Hechiche M, Ben Romdhane K, Boussen H, Saadi A, Achour N, Ben Ayed F

机构信息

Institut Salah Azaiez.

出版信息

Tunis Med. 2009 Jul;87(7):417-25.

PMID:20063673
Abstract

The goal of this study is to analyze certain epidemiologic characteristics of breast cancer in Tunisia and to foresee the consequences that will arise from the trends in incidence of this cancer. Data obtained from the North-Tunisia Cancer Registry (NTCR) and from the Salah AZAIZ Institute (SAI) Registry is used to estimate the different incidence rates and to compare these rates with those of other countries. In 15 years the crude incidence rate for breast cancer in the North Tunisia almost doubled to reach 21.5 cases/100,000 women per year during 1994-1998. The high rate of this cancer among women younger than 35 years (11%) could be related to a relatively low incidence among post-menopausal women. The clinical profile of breast cancer remains quite alarming: 40.2% of cases have a tumor with a clinical diameter equal or greater than 5 cm. Birth cohort effect, also know as the generation effect, is expected to lead to an increase of cancer incidence in the future. The rather high number of young cases is a source of additional cost on social and financial level. The priority is now to solve the problem of late diagnosis it has aggravated the prognosis of this cancer in Tunisia.

摘要

本研究的目的是分析突尼斯乳腺癌的某些流行病学特征,并预测该癌症发病率趋势将产生的后果。从北突尼斯癌症登记处(NTCR)和萨拉赫·阿扎伊兹研究所(SAI)登记处获得的数据用于估计不同的发病率,并将这些发病率与其他国家的发病率进行比较。在15年里,北突尼斯乳腺癌的粗发病率几乎翻了一番,在1994 - 1998年期间达到每年每10万名女性中有21.5例。35岁以下女性中这种癌症的高发病率(11%)可能与绝经后女性相对较低的发病率有关。乳腺癌的临床特征仍然相当令人担忧:40.2%的病例肿瘤临床直径等于或大于5厘米。出生队列效应,也称为代际效应,预计未来会导致癌症发病率上升。相当数量的年轻病例在社会和经济层面带来了额外成本。现在的首要任务是解决晚期诊断问题,它恶化了突尼斯这种癌症的预后。

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