Ling R, James B
Eye Unit, Stoke Mandeville Hospital, Aylesbury, Bucks, UK.
Postgrad Med J. 1998 Oct;74(876):581-2. doi: 10.1136/pgmj.74.876.581.
Roth spots (white-centred retinal haemorrhages) were classically described as septic emboli lodged in the retina of patients with subacute bacterial endocarditis. Indeed many have considered Roth spots pathognomonic for this condition. More recent histological evidence suggests, however, that they are not foci of bacterial abscess. Instead, they are nonspecific and may be found in many other diseases. A review of the histology and the pathogenesis of these white-centred haemorrhages will be provided, along with the work-up of the differential diagnosis.
Roth斑（中心白色的视网膜出血）传统上被描述为亚急性细菌性心内膜炎患者视网膜中滞留的脓毒性栓子。的确，许多人认为Roth斑是这种疾病的特征性表现。然而，最近的组织学证据表明，它们并非细菌性脓肿病灶。相反，它们是非特异性的，可能在许多其他疾病中出现。本文将对这些中心白色出血的组织学和发病机制进行综述，并介绍鉴别诊断的检查方法。
