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红细胞在化疗药物药代动力学中的作用。

Role of red blood cells in pharmacokinetics of chemotherapeutic agents.

作者信息

Schrijvers D, Highley M, De Bruyn E, Van Oosterom A T, Vermorken J B

机构信息

Department of Medical Oncology, University Hospital Antwerp, Edegem, Belgium.

出版信息

Anticancer Drugs. 1999 Feb;10(2):147-53. doi: 10.1097/00001813-199902000-00002.

DOI:10.1097/00001813-199902000-00002
PMID:10211544
Abstract

After oral or parenteral administration of chemotherapeutic agents, these drugs are transported to the tissues by the blood in different fractions: plasma water, plasma proteins or cells. In this review, the role of the red blood cell in storage, transport and metabolism of different anti-cancer drugs is described.

摘要

在口服或胃肠外给予化疗药物后,这些药物以不同的组分通过血液转运至组织:血浆水、血浆蛋白或细胞。在本综述中,描述了红细胞在不同抗癌药物的储存、转运和代谢中的作用。

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