Pearson G R, Day M J, Main D, Pawade J
Department of Pathology and Microbiology, University of Bristol Veterinary School, Langford, BS40 7DU, UK.
J Comp Pathol. 1999 Apr;120(3):295-9. doi: 10.1053/jcpa.1998.0244.
A lymphoma affecting the synovia was identified in both tarsal joints of an aged sheep. With a panel of cross-reactive antibodies specific for lambda and kappa immunoglobulin light chain, MHC class II, CD3, CD79a and the Ki-67 antigen, the neoplasm was classified as a B-cell lymphoma with uniform expression of surface membrane CD79a. This would seem to be the first report of a lymphoma affecting the synovia in a domestic animal, and the first use of the CD79a reagent on ovine tissue.
