乔瓦尼·巴蒂斯塔·莫尔加尼，临床肾脏病学的先驱。

Giovan Battista Morgagni, a pioneer of clinical nephrology.

作者信息

Antonello A, Calò L, Bonfante L, Mennella G, Abaterusso C, Spinello M, Favaro S, D'Angelo A

机构信息

Institute of Internal Medicine, Division of Nephrology, University of Padova, Italy.

出版信息

Am J Nephrol. 1999;19(2):222-5. doi: 10.1159/000013454.

DOI:10.1159/000013454

PMID:10213822

Abstract

In the 18th century, Giovanni Battista Morgagni was the first to propose that specific signs and symptoms are linked to particular anatomical changes at autopsy and that these changes were the cause of the disease. This paper describes the report by Morgagni wherein he linked the anatomic findings at autopsy, specifically atrophied kidneys, with the signs and symptoms of a disease now known as uremia. From these findings, Morgagni felt that he had identified the factors responsible for the disease as well as its clinical course.

摘要

在18世纪，乔瓦尼·巴蒂斯塔·莫尔加尼首次提出，特定的体征和症状与尸检时特定的解剖学变化有关，且这些变化是疾病的病因。本文描述了莫尔加尼的报告，其中他将尸检时的解剖学发现，特别是萎缩的肾脏，与一种现在称为尿毒症的疾病的体征和症状联系起来。基于这些发现，莫尔加尼认为他已经确定了导致该疾病的因素及其临床病程。