De Broe M E, De Weerdt D L, Ysebaert D K, Vercauteren S R, De Greef K E, De Broe L C
Department of Nephrology, University of Antwerp, Belgium.
Am J Nephrol. 1999;19(2):282-9. doi: 10.1159/000013462.
Andreas Vesalius and Jan Baptist Van Helmont are the two major personalities who contributed substantially and in a different way to the early development of renal anatomy/physiology of the 16th/17th century in the Southern Low Countries. The importance of A. Vesalius' publication 'de humani corporis fabrica libri septem' cannot be overestimated. The kidney was an intriguing organ to Vesalius, the function of which he could not fully grasp. J.B. Van Helmont was the first to demonstrate the importance of the measurement of the specific gravity of the urine and relating it to physiological and pathophysiological conditions. He made accurate clinical observations supported by autopsy examinations concerning the role of the kidney in the generation of dropsy.
安德烈亚斯·维萨里（Andreas Vesalius）和扬·巴普蒂斯塔·范·海尔蒙特（Jan Baptist Van Helmont）是两位对16/17世纪低地国家南部肾脏解剖学/生理学的早期发展做出重大且不同贡献的主要人物。安德烈亚斯·维萨里所著的《人体的构造》（'de humani corporis fabrica libri septem'）的重要性怎么高估都不为过。肾脏对维萨里来说是一个引人入胜的器官，其功能他无法完全理解。扬·巴普蒂斯塔·范·海尔蒙特是第一个证明测量尿液比重并将其与生理和病理生理状况相关联的重要性的人。他通过尸检支持进行了准确的临床观察，涉及肾脏在水肿形成中的作用。
