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[不同年龄大鼠运动防御性条件反射的形成与发展]

[Formation and development of motor-defense conditioned reflexes in rats of different ages].

作者信息

Georgieva N

出版信息

Eksp Med Morfol. 1976;15(3):145-51.

PMID:1021408
Abstract

The analysis of the reflex conditioned activity of rats at various age groups showed that there were differences in it. There was a considerable strength of the excitatory process in young rats, aged one and a half months. The positive reflexes to sound and light stimuli were formed compatively quickly (on the average after 8,6 and 4,8 combinations of the conditioned stimulus with the unconditioned stimulus) in comparison with the animals of mature age (respectively 16,5 and 8 combinations). In the old rats the author observed a lowering of the strength of the excitatory process and slower formation and stabilization of the positive conditioned reflexes. A gradual formation of the inhibitory function occurs during the process of ontogenetic development and this finds an expression in the unpossibility for the fromation of differentiation in young animals and the presence of such in 10-month old rats. The level of the differentiations in these animals reached 60,1% and 76,9%. The latent period changed with the advancement of age. In adult animals there was some shortenint ofthelatent period in comparison with the young animals although the difference was statistically insignificant. There was an increase of the absolute values of the latent period again after the occurrence of the old age (5,2'' and 4,52''). The indicated peculiarities in the formation and course of the conditioned reflexes probably were connected with various degree in the fluctuations of the strength of the exitiatory and inhibitory processes in the central nervous system during ontogenesis.

摘要

对不同年龄组大鼠的反射性条件活动进行分析表明,其中存在差异。在1个半月大的幼鼠中,兴奋过程的强度相当大。与成年动物(分别为16.5次和8次)相比,幼鼠对声音和光刺激的阳性反射形成得相对较快(条件刺激与非条件刺激平均经过8.6次和4.8次组合)。在老年大鼠中,作者观察到兴奋过程的强度降低,阳性条件反射的形成和稳定较慢。抑制功能在个体发育过程中逐渐形成,这表现为幼小动物无法形成分化,而10个月大的大鼠则存在分化,这些动物的分化水平分别达到60.1%和76.9%。潜伏期随年龄增长而变化。与幼小动物相比,成年动物的潜伏期有所缩短,尽管差异在统计学上不显著。老年期(5.2秒和4.52秒)出现后,潜伏期的绝对值再次增加。条件反射形成和过程中的上述特点可能与个体发育过程中中枢神经系统兴奋和抑制过程强度波动的不同程度有关。

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