Ortega P, Gil A, Astasio P, Domínguez V, Ramón de Juanes J, Arrazola P, González A
Departamento de Medicina Preventiva, Facultad de Medicina, Universidad Complutense de Madrid.
Enferm Infecc Microbiol Clin. 1999 Mar;17(3):135-7.
The aim of the present study was to determine the prevalence of antibodies versus tetanus, diphtheria and Bordetella pertussis in a population of health care personnel.
A transversal study was carried out in a population of healthy health care professionals from two hospitalary centers in the Community of Madrid (Spain). The ELISA method was used for antibody determinations. The determination of antibodies versus tetanus and diphtheria was performed in a total of 344 individuals (mean age 32 years) and that of whooping cough in 104 subjects (mean age 23 years).
The global prevalence of tetanus, diphtheria and whooping cough was of 76.5, 48 and 57%, respectively. The prevalence of antibodies versus tetanus was significantly greater in males than in females.
Revaccination versus tetanus and diphtheria is recommended every 10 years to guarantee protector antibody concentrations in adults. With regard to whooping cough, revaccination could be a strategy to consider in the future, particularly in risk groups in contact with cases of this disease.
本研究的目的是确定医护人员群体中破伤风、白喉和百日咳抗体的流行情况。
在西班牙马德里自治区两个医院中心的健康医护专业人员群体中开展了一项横断面研究。采用酶联免疫吸附测定(ELISA)法进行抗体测定。共对344名个体(平均年龄32岁)进行了破伤风和白喉抗体测定,对104名受试者(平均年龄23岁)进行了百日咳抗体测定。
破伤风、白喉和百日咳抗体的总体流行率分别为76.5%、48%和57%。男性破伤风抗体流行率显著高于女性。
建议每10年进行一次破伤风和白喉再接种,以确保成年人中保护性抗体浓度。关于百日咳,未来再接种可能是一种可考虑的策略,特别是在接触该病病例的高危人群中。