Zwieb C, Wower I, Wower J
Department of Molecular Biology, The University of Texas Health Science Center at Tyler, 11937 US Highway 271, Tyler, TX 75708-3154, USA.
Nucleic Acids Res. 1999 May 15;27(10):2063-71. doi: 10.1093/nar/27.10.2063.
Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudoknotted regions.
细菌和质体转移信使核糖核酸(tmRNA)的最小二级结构是通过对50条比对的tmRNA序列进行比较分析得出的。这些结构包括12个螺旋和4个假结,是早期版本的改进,但只包括有比较证据的碱基对。文中描述了来自广泛系统发育谱系的tmRNA的保守和可变特征、细菌亚群特有的结构特性以及来自假结区域的初步三维模型。