Williams R L, Fukui M B, Meltzer C C, Swarnkar A, Johnson D W, Welch W
Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA.
AJNR Am J Neuroradiol. 1999 Mar;20(3):381-5.
The MR imaging findings of fungal spinal osteomyelitis in three recipients of organ transplants showed hypointensity of the vertebral bodies on T1-weighted sequences in all cases. Signal changes and enhancement extended into the posterior elements in two cases. Multiple-level disease was present in two cases (with a total of five intervertebral disks involved in three cases). All cases lacked hyperintensity within the disks on T2-weighted images. In addition, the intranuclear cleft was preserved in four of five affected disks at initial MR imaging. MR features in Candida and Aspergillus spondylitis that are distinct from pyogenic osteomyelitis include absence of disk hyperintensity and preservation of the intranuclear cleft on T2-weighted images. Prompt recognition of these findings may avoid delay in establishing a diagnosis and instituting treatment of opportunistic osteomyelitis in the immunocompromised patient.
三名器官移植受者的真菌性脊柱骨髓炎的磁共振成像(MR)表现显示,所有病例在T1加权序列上椎体均呈低信号。两例病例的信号改变和强化延伸至后部结构。两例病例存在多节段病变(三例共累及五个椎间盘)。所有病例在T2加权图像上椎间盘内均无高信号。此外,在最初的MR成像中,五个受累椎间盘中有四个保留了核内裂隙。念珠菌和曲霉菌脊柱炎的MR特征与化脓性骨髓炎不同,包括T2加权图像上椎间盘无高信号以及核内裂隙保留。及时识别这些表现可避免免疫功能低下患者在诊断机会性骨髓炎和开始治疗方面出现延误。