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使用6F引导导管和低剂量肝素进行冠状动脉血管成形术和支架置入术后两小时下床活动。

Two hour ambulation after coronary angioplasty and stenting with 6 F guiding catheters and low dose heparin.

作者信息

Koch K T, Piek J J, de Winter R J, Mulder K, Schotborgh C E, Tijssen J G, Lie K I

机构信息

Department of Cardiology, B2-136, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands.

出版信息

Heart. 1999 Jan;81(1):53-6. doi: 10.1136/hrt.81.1.53.

Abstract

OBJECTIVE

To evaluate the feasibility and safety of ambulation of patients two hours after elective coronary angioplasty or stenting, or both.

METHODS

Coronary angioplasty and stenting were performed using 6 F guiding catheters by the femoral approach and a standard dose of heparin 5000 IU. There were no angiographic exclusion criteria except for planned atherectomy. Patients given oral anticoagulants or heparin were not eligible. All patients were given aspirin. Patients who underwent stent implantation also received ticlopidine 250 mg daily. The arterial sheath was removed immediately after the procedure. Haemostasis was achieved by manual compression and maintained with an inguinal compression bandage. Early ambulation was attempted after two hours of supine bed rest following removal of the bandage.

MAIN OUTCOME MEASURES

The incidence of bleeding at or during ambulation requiring compression and additional bed rest, and puncture site complications documented 48 hours after the procedure.

RESULTS

300 of 359 consecutive eligible patients were included for two hour ambulation. Stent implantation was performed in 32% of the procedures. The mean (SD) time to haemostasis was 9.6 (3.2) minutes. Bleeding at ambulation occurred in five patients (1.7%), and nine patients (3.0%) reached the secondary end point of haematoma > 5 x 5 cm at 48 hour follow up. All were treated conservatively without further sequelae. There was no late bleeding or vascular complications.

CONCLUSION

Ambulation two hours after elective balloon angioplasty or stent implantation with 6 F guiding catheters by the femoral route and low dose heparin is feasible and safe, with a low incidence of puncture site complications. This early ambulation protocol facilitates a short hospital stay.

摘要

目的

评估择期冠状动脉血管成形术或支架置入术(或两者皆有)后两小时让患者下床活动的可行性和安全性。

方法

采用6F引导导管经股动脉途径进行冠状动脉血管成形术和支架置入术,并给予标准剂量的5000IU肝素。除计划进行旋切术外,无血管造影排除标准。正在服用口服抗凝剂或肝素的患者不符合条件。所有患者均服用阿司匹林。接受支架植入的患者还每日服用250mg噻氯匹定。术后立即拔除动脉鞘管。通过手动压迫实现止血,并用腹股沟压迫绷带维持。在拆除绷带后仰卧卧床休息两小时后尝试早期下床活动。

主要观察指标

下床活动时或活动期间需要压迫止血及额外卧床休息的出血发生率,以及术后48小时记录的穿刺部位并发症。

结果

359例连续符合条件的患者中有300例纳入两小时下床活动研究。32%的手术进行了支架植入。止血的平均(标准差)时间为9.6(3.2)分钟。5例患者(1.7%)在活动时出血,9例患者(3.0%)在48小时随访时达到血肿>5×5cm的次要终点。所有患者均接受保守治疗,无进一步后遗症。无晚期出血或血管并发症。

结论

经股动脉途径使用6F引导导管及低剂量肝素进行择期球囊血管成形术或支架植入术后两小时下床活动是可行且安全的,穿刺部位并发症发生率低。这种早期下床活动方案有助于缩短住院时间。

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本文引用的文献

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Early ambulation after coronary angioplasty and stenting with six French guiding catheters and low-dose heparin.
Am J Cardiol. 1997 Oct 15;80(8):1084-6. doi: 10.1016/s0002-9149(97)00609-7.
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J Am Coll Cardiol. 1997 Feb;29(2):323-7. doi: 10.1016/s0735-1097(96)00486-x.
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