[无原发性皮肤受累的外周T细胞淋巴瘤。29例连续病例的解剖临床研究]
[Peripheral T-cell lymphomas without primary skin involvement. An anatomicoclinical study of 29 consecutive cases].
作者信息
Salar A, Fernández de Sevilla A, Romagosa V, Domingo-Claros A, González-Barca E, Grañena A
机构信息
Servicio de Hematología Clínica, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona.
出版信息
Med Clin (Barc). 1999 Feb 27;112(7):255-6.
BACKGROUND
To analyze peripheral non-cutaneous T-cell lymphomas (NC-TCL) and to test the significance of the IPI.
PATIENTS AND METHODS
Twenty-nine consecutive patients diagnosed with NC-TCL according to the REAL classification.
RESULTS
At diagnosis were common: B symptoms (21%), stage III/IV (55%), high LDH level (55%) and extranodal involvement (79%). Twelve (48%) patients achieved complete remission. The IPI identified groups of patients with different response to therapy and survival.
CONCLUSIONS
NC-TCL with high or high-intermediate IPI had a short survival if treated with CHOP.
背景
分析外周非皮肤T细胞淋巴瘤（NC-TCL）并检验国际预后指数（IPI）的意义。
患者与方法
根据REAL分类法，连续纳入29例诊断为NC-TCL的患者。
结果
诊断时常见情况如下：B症状（21%）、Ⅲ/Ⅳ期（55%）、乳酸脱氢酶（LDH）水平升高（55%）及结外受累（79%）。12例（48%）患者达到完全缓解。IPI可区分对治疗反应及生存情况不同的患者组。
结论
CHOP方案治疗时，IPI为高危或高中危的NC-TCL患者生存期短。
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