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健康受试者、冠状动脉粥样硬化患者及风湿性心脏病患者的动脉血和静脉血的凝固性。

Coagulability of arterial and venous blood in healthy subjects, patients with coronary atherosclerosis, and patients with rheumatic cardiopathies.

作者信息

Saveleva T V, Kuznik B I, Goldentsvaig Y D

出版信息

Cor Vasa. 1976;18(4):249-57.

PMID:1022402
Abstract

Coagulability of arterial and venous blood was studied in 50 healthy subjects and in 179 patients with circulation disturbances caused by coronary atherosclerosis and rheumatic cardiopathies. All indicators characterizing the individual haemocoagulation phases were respected. In the healthy subjects the coagulative and fibrinolytic activities of venous blood were higher than those of arterial blood. In the patients with heart failure the coagulability of venous blood decreased and that of arterial blood increased. These phenomena were accompanied by fibrinogenaemia, appearance of fibrinogen B in the blood, elevation of free heparin, and inhibition, but occasional activation, of fibrinolysis in both vascular systems. The findings seem to signalize enhanced intravascular blood coagulability in patients with circulation disturbances, which phenomenon has to be taken into account in the treatment of such patients.

摘要

对50名健康受试者以及179名患有冠状动脉粥样硬化和风湿性心脏病引起的循环障碍患者的动静脉血液凝固性进行了研究。所有表征各个血液凝固阶段的指标均受到关注。在健康受试者中,静脉血的凝固和纤溶活性高于动脉血。心力衰竭患者静脉血的凝固性降低,动脉血的凝固性增加。这些现象伴随着纤维蛋白原血症、血液中纤维蛋白原B的出现、游离肝素的升高以及两个血管系统中纤溶的抑制,但偶尔也有激活。这些发现似乎表明循环障碍患者血管内血液凝固性增强,在治疗此类患者时必须考虑到这一现象。

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1
Coagulability of arterial and venous blood in healthy subjects, patients with coronary atherosclerosis, and patients with rheumatic cardiopathies.健康受试者、冠状动脉粥样硬化患者及风湿性心脏病患者的动脉血和静脉血的凝固性。
Cor Vasa. 1976;18(4):249-57.
2
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