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心肌梗死的医院预后与危险因素的关系。

Hospital prognosis of myocardial infarction with respect to risk factors.

作者信息

Zdichynec B

出版信息

Cor Vasa. 1976;18(4):294-8.

PMID:1022408
Abstract

Out of 9922 patients with ischaemic heart disease [IHD] hospitalized during a decade, clinico-pathological data of 796 patients with acute myocardial infarction [MI] were analyzed in detail. With the aid of a logico-probabilistic model, the author made an attempt to quantify the individual risks of the hospital prognosis of MI and to obtain the so-called cumulative risk of MI. The prognostic relevances of the characters investigated were tested by Bayes' theorem. By reducing the matrix "character-disease", the original number of 201 characters was reduced to 34, which were divided into five classes, as follows: a] anamnestic data about the occurrence of risk factors, b] data on coronary pains, c] objective clinical, electrocardiographic, or roentgenological findings, d] duration of the praehospitalization phase, e] patient's sex and age. The cumulative risk [sum of partial risks] amounted to 60% and less in MI with a favourable hospital prognosis [that is, at lethality lesser than 5%]; to 61%--100% with a medium fair hospital prognosis [at lethality from 6% to 30%], and to more than 101% with a poor hospital prognosis [at lethality of 41% and higher]. A comparative test of the prognostic index, performed in a different referral area, showed a relatively good practical usability of the criteria described.

摘要

在十年间住院的9922例缺血性心脏病(IHD)患者中,对796例急性心肌梗死(MI)患者的临床病理数据进行了详细分析。借助逻辑概率模型,作者试图量化MI患者医院预后的个体风险,并得出所谓的MI累积风险。通过贝叶斯定理检验所研究特征的预后相关性。通过简化“特征-疾病”矩阵,将原来的201个特征减少到34个,这些特征分为五类,如下:a]关于危险因素发生的既往史数据;b]关于冠状动脉疼痛的数据;c]客观临床、心电图或放射学检查结果;d]院前阶段的持续时间;e]患者的性别和年龄。在医院预后良好(即死亡率低于5%)的MI患者中,累积风险(部分风险之和)为60%及以下;在医院预后中等(死亡率为6%至30%)的患者中,累积风险为61% - 100%;在医院预后较差(死亡率为41%及更高)的患者中,累积风险超过101%。在不同转诊地区对预后指数进行的对比测试表明,所描述的标准具有相对良好的实际可用性。

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