Veselovskaia N V, Savchuk S A, Izotov B N
Sud Med Ekspert. 1999 Mar-Apr;42(2):20-5.
Reviews data on analysis of narcotic phencyclidine and its main metabolites and analogs. Pharmacological and toxic characteristics of phencyclidine, conditions of its isolation from biological objects and its detection and measurement by thin layer and gas chromatography and by chromatographic mass-spectrometry are described. Analysis of phencyclidine metabolites is discussed and a scheme of its metabolism is presented. Statistical characteristics of methods of quantitative analysis of phencyclidine in biological objects are presented.
综述了关于麻醉药苯环利定及其主要代谢物和类似物分析的数据。描述了苯环利定的药理和毒理学特性、从生物样品中分离它的条件以及通过薄层色谱、气相色谱和色谱 - 质谱联用对其进行检测和测量的方法。讨论了苯环利定代谢物的分析，并给出了其代谢示意图。介绍了生物样品中苯环利定定量分析方法的统计学特征。
