Tamura-Takahashi H, Ui N
Endocrinol Jpn. 1976 Dec;23(6):511-6. doi: 10.1507/endocrj1954.23.511.
Properties of the four purified components of whale thyroid-stimulating hormone (TSH) have been compared. The amino acid composition shows close similarity among these components. Their hexosamine and sialic acid contents are of the same magnitude, whereas the neutral sugar composition differs somewhat from each other. The molecular weight of whale TSH determined by sedimentation equilibrium is 29,000, and no difference in molecular weight as well as in Stokes radius as determined by gel filtration has been detected among these four components. The amino acid and carbohydrate compositions of whale TSH resemble those of TSH from other species, especially those of non-primate mammalian TSH. Whale TSH contains, unlike bovine TSH but like human TSH, 1-2 residues of sialic acid as a constituent carbohydrate.
对鲸促甲状腺激素（TSH）的四种纯化组分的特性进行了比较。这些组分的氨基酸组成显示出密切的相似性。它们的己糖胺和唾液酸含量处于相同水平，而中性糖组成彼此略有不同。通过沉降平衡测定的鲸TSH分子量为29,000，在这四种组分中未检测到分子量以及通过凝胶过滤测定的斯托克斯半径有差异。鲸TSH的氨基酸和碳水化合物组成与其他物种的TSH相似，尤其是非灵长类哺乳动物的TSH。与牛TSH不同但与人TSH一样，鲸TSH含有1-2个唾液酸残基作为组成碳水化合物。
