[全身性惊厥发作情况下的脑胆碱酯酶]
[Cerebral cholinesterase under conditions of a generalized convulsive seizure].
作者信息
Shelikhov V N, Chernyshevskaia I A, Korotich V A
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1976 Nov;62(11):1572-7.
PMID:1022530
Abstract
The activity of acetylcholinesterase and butyrilcholinesterase was studied during prolonged seizures developing from a primary-cortical focus. The activity was found to spread both along the wide limbic system, which indicates to participation of cholinergic agents in processes of "recurrent generalization" of excitations, and along the horizontal system of fibers connecting both hemispheres. This latter finding indicates to participation of cholinergic mediatory mechanisms in formation of seizures.
摘要
在由原发性皮质病灶引发的持续性癫痫发作期间，对乙酰胆碱酯酶和丁酰胆碱酯酶的活性进行了研究。发现该活性沿着广泛的边缘系统扩散，这表明胆碱能介质参与了兴奋的“反复泛化”过程，并且沿着连接两个半球的纤维水平系统扩散。后一发现表明胆碱能介导机制参与了癫痫发作的形成。
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