Lowell J A, Coopersmith C M, Shenoy S, Howard T K
Section of Transplantation, Washington University School of Medicine, St Louis, MO, USA.
Liver Transpl Surg. 1999 May;5(3):200-3. doi: 10.1002/lt.500050306.
The clinical presentation and causes of hepatic artery pseudoaneurysm vary widely in the postoperative liver transplant recipient, although infection is the most common cause. Although uncommon, hepatic artery complications continue to be an important source of morbidity in liver transplant recipients. Thrombosis, stenosis, and pseudoaneurysm formation are the most common posttransplantation arterial complications. Pseudoaneurysms are most commonly mycotic in origin. Prompt recognition of hepatic artery pseudoaneurysms with aggressive intervention (both surgical and angiographic) may decrease the morbidity associated with this rare clinical entity. The records of 263 consecutive patients who underwent orthotopic liver transplantation between 1991 and 1996 were reviewed retrospectively and assessed for hepatic artery complications. Two patients (0.7%) developed hepatic artery pseudoaneurysm, neither associated with infection. Both patients required operative repair and are doing well without vascular complications at a mean follow-up of 22.5 months. The clinical presentation and causes of hepatic artery pseudoaneurysm vary widely in the postoperative liver transplant recipient. Prompt recognition of hepatic artery pseudoaneurysms with aggressive intervention (both surgical and angiographic) may decrease the morbidity associated with this rare clinical entity.
肝动脉假性动脉瘤在肝移植术后受者中的临床表现和病因差异很大,尽管感染是最常见的病因。肝动脉并发症虽不常见,但仍是肝移植受者发病的重要原因。血栓形成、狭窄和假性动脉瘤形成是移植后最常见的动脉并发症。假性动脉瘤最常见的起源是感染性。及时识别肝动脉假性动脉瘤并积极干预(包括手术和血管造影)可能会降低与这种罕见临床病症相关的发病率。回顾性分析了1991年至1996年间连续263例行原位肝移植患者的记录,并评估肝动脉并发症情况。两名患者(0.7%)发生了肝动脉假性动脉瘤,均与感染无关。两名患者均需手术修复,平均随访22.5个月,目前情况良好,无血管并发症。肝动脉假性动脉瘤在肝移植术后受者中的临床表现和病因差异很大。及时识别肝动脉假性动脉瘤并积极干预(包括手术和血管造影)可能会降低与这种罕见临床病症相关的发病率。