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肝移植术后肝动脉霉菌性动脉瘤

Post-liver transplant mycotic aneurysm of the hepatic artery.

作者信息

Jones Vinci S, Chennapragada Murthy S, Lord David J E, Stormon Michael, Shun Albert

机构信息

Department of Pediatric Surgery, The Children's Hospital at Westmead, Westmead, Sydney 2145, NSW, Australia.

出版信息

J Pediatr Surg. 2008 Mar;43(3):555-8. doi: 10.1016/j.jpedsurg.2007.10.061.

Abstract

BACKGROUND

Mycotic aneurysm of the hepatic artery is a rare complication of liver transplantation, occurring in 0% to 3% of patients and having a mortality of around 30%. We present a unique report of mycotic aneurysms of the hepatic artery following liver transplantation in children.

METHODS AND RESULTS

A chart review of the 194 patients who underwent a liver transplantation over a 21-year period revealed 2 patients who developed a mycotic aneurysm of the hepatic artery. The first patient died due to rupture prior to diagnosis. The second patient was treated successfully using radiological coil embolization, followed by surgical excision with hepatic artery ligation and antibiotic therapy.

CONCLUSIONS

Early diagnosis and prompt multidisciplinary treatment is crucial to optimize treatment in this condition.

摘要

背景

肝动脉真菌性动脉瘤是肝移植罕见的并发症,发生率为0%至3%,死亡率约为30%。我们报告了一例儿童肝移植后发生肝动脉真菌性动脉瘤的独特病例。

方法与结果

对194例在21年期间接受肝移植的患者进行病历回顾,发现2例发生肝动脉真菌性动脉瘤。第一例患者在诊断前因破裂死亡。第二例患者通过放射线圈栓塞术成功治疗,随后进行肝动脉结扎手术切除并给予抗生素治疗。

结论

早期诊断和及时的多学科治疗对于优化这种疾病的治疗至关重要。

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