Bauer A, Alsen-Hinrichs C, Wassermann O
Institut für Toxikologie, Klinikum Christian-Albrechts-Universität zu Kiel.
Gesundheitswesen. 1999 Feb;61(2):93-100.
Cancer mortality in two counties (Dithmarschen and Nordfriesland) of the Federal State of Schleswig-Holstein (Germany) was assessed by analysing the death certificates for the period from 1980 to 1991. Age-adjusted cancer mortality rates were calculated for the more common cancers for counties as well as for smaller sub-scales. The procedure in respect of data base, data protection, data flow, calculation of rates and mapping of cancer mortality rates on small geographic scales is described and discussed. The data collected by us was compared with the data provided by the offices of statistic affairs on a county scale (only for the more common cancers). The comparison was done for each gender and each county, respectively. The agreement was high (> 95%) for 16 of 22 compared items, and below 90% for two items only. The validity of the data, therefore, was considered sufficient for epidemiological studies. As an example, results regarding female breast cancer rates are shown. The possibilities for the utilization of cancer registries on small geographic scales are discussed: Depending on the incidence of the occurrence of different cancers, cancer registries should provide data on multiple regional scales. A more flexible use of the possibilities of the assessment of regional cancer rates is imperative to utilise the very expensive and time-consuming instruments of analytical epidemiological studies of the causes of cancer more effectively.
通过分析1980年至1991年期间的死亡证明，对德国石勒苏益格－荷尔斯泰因州的两个县（迪特马尔申县和北弗里斯兰县）的癌症死亡率进行了评估。计算了各县以及较小子区域中较常见癌症的年龄调整癌症死亡率。描述并讨论了有关数据库、数据保护、数据流、率的计算以及小地理尺度上癌症死亡率映射的程序。将我们收集的数据与统计事务办公室在县一级提供的数据（仅针对较常见癌症）进行了比较。分别针对每个性别和每个县进行了比较。在22个比较项目中，有16个的一致性较高（>95%），只有两个项目低于90%。因此，认为这些数据的有效性足以用于流行病学研究。作为示例，展示了女性乳腺癌率的结果。讨论了在小地理尺度上利用癌症登记处的可能性：根据不同癌症发生的发病率，癌症登记处应在多个区域尺度上提供数据。更灵活地利用评估区域癌症率的可能性对于更有效地利用分析癌症病因的非常昂贵且耗时的流行病学研究工具至关重要。
