Namiki K, Tsuchiya A, Noda K, Oyama H, Ishibashi K, Kusama H, Furusato M
Department of Urology, Tokyo Medical University, Japan.
Int J Urol. 1999 Mar;6(3):158-61. doi: 10.1046/j.1442-2042.1999.06314.x.
We report on a case of extragonadal germ cell tumor of the prostate associated with Klinefelter's syndrome.
METHODS/RESULTS: The patient was a 33-year-old man. A transrectal prostate biopsy suggested combined germ cell tumor (yolk sac tumor + teratoma). Because there was no tumor except from the prostate, we considered this case to be a primary extragonadal germ cell tumor of the prostate. The prostate tumor responded to systemic chemotherapy with cisplatin, vinblastine and bleomycin and elevated lactate dehydrogenase and alpha-fetoprotein levels normalized. In addition to chemotherapy, the patient also underwent radiation therapy.
The patient has survived for approximately 4 years since the diagnosis.
