Brilakis E S, Young W F, Wilson J W, Thompson G B, Munger T M
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
J Heart Lung Transplant. 1999 Apr;18(4):376-80. doi: 10.1016/s1053-2498(98)00014-x.
Both dilated and hypertrophic cardiomyopathy have been reported in patients with pheochromocytoma, who were almost always hypertensive. The outcome frequently has been fatal, yet cardiac dysfunction can be reversible after medical or surgical therapy for the pheochromocytoma.
We report the case of a patient with dilated cardiomyopathy without persistent or paroxysmal hypertension, who was found to have a pheochromocytoma during initial medical evaluation.
The identification and treatment of the pheochromocytoma led to significant improvement in cardiac function and cardiac transplantation was avoided.
This case illustrates some unusual features in pheochromocytoma-induced cardiomyopathy: (1) absence of persistent or paroxysmal hypertension, (2) initial presentation with acute myocardial infarction and normal coronary arteries, and (3) recurrent episodes of nonsustained ventricular tachycardia.
据报道,嗜铬细胞瘤患者可出现扩张型和肥厚型心肌病,这些患者几乎均有高血压。其结局往往是致命的,然而,针对嗜铬细胞瘤进行内科或外科治疗后,心脏功能障碍可能可逆。
我们报告一例扩张型心肌病患者,该患者无持续性或阵发性高血压,在初次医学评估时发现患有嗜铬细胞瘤。
嗜铬细胞瘤的识别与治疗使心脏功能显著改善,避免了心脏移植。
该病例说明了嗜铬细胞瘤诱发的心肌病的一些不寻常特征:(1)无持续性或阵发性高血压;(2)最初表现为急性心肌梗死且冠状动脉正常;(3)非持续性室性心动过速反复发作。